One thing I do love about owning a 'classic' car is they will provide hours of hobby time. Few daze ago I heard a knocking sound from underneath the passengers seat. It was intermittent and matched the engine rpm not tire rotation. Quick investigation, the fuel line from tank to pump was pulsating and hitting front frame rail. Has anyone else had a knocking fuel line? Thinking fuel pump. I replaced it years ago to get it started/home when first bought car. Clogged fuel filter causing back pressure? A loose frame/fuel line clamp? They seemed tight. Should I replace the whole line set-up? It's original. Would up-sizing to 3/8 be advantageous? Running a Holley 390. It does have newer sending unit, what sends incorrect fuel levels. Would dropping the tank and adjusting the float arm be reasonable fix for level readings. I know about the sender/gauge adjustment box but like trying free ways first. Car runs excellent beyond the tapping. Anyways I'm retired and have hobby time. Thank you

Adjust the position of the line slightly so it can't hit the frame there, securing it as needed, and/or put a slit length of fuel line hose over it to prevent metal-to-metal contact.
Probably not.
I can't imagine why. Not even slightly, no.
Depends on what kind of inaccuracy you're seeing. If the resistance curve is correct but shifted in one direction or the other, bending the arm couild fix it. If the resistance curve is wrong, then only a sender with the appropriate curve will fix it.

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Too many people who were born on third base actually believe they've hit a triple.

I have seen what you are describing one time. But it is certainly not a valid comparison. I saw an engine mounted direct injection HIGH pressure fuel pump cause the front to rear fuel feed line to vibrate loud enough to hear it in the car. You could watch that line dancing whenever the engine was on.

New pump did get rid of the vibration. But the HIGH pressure pump I replaced operates at 1000+ psi at times so I don't think it is an apples to apples situation. Regardless of if it is caused by you fuel pump, you might end up having a hard time getting a good slant fuel pump from the parts store. If you run correctly on the current pump I would try to better isolate/mount the hard line to prevent movement.

Another option that isn't NHRA approved would be to get an extra long section of fuel hose (quality fuel hose) and run a circular loop of it from the fuel pump to the metal line. This loop would need to be properly secured but should absorb the pulses. If you go this route it needs good mounting/routing to protect the hose, fuel is not something you want leaking.